ID (ISN) del documento | 21858 |
Número CIS |
74-1926 |
ISSN - Título de la serie |
0003-9896 - Archives of Environmental Health |
Año |
1974 |
Número de serie |
|
Autor(es) |
Traiger G.J., Plaa G.L. |
Título |
Chlorinated hydrocarbon toxicity - Potentiation by isopropyl alcohol and acetone. |
Información bibliográfica |
May 1974, Vol.28, No.5, p.276-278. 10 ref. |
Resumen |
In experiments with mice it was shown that pre-treatment with isopropyl alcohol or acetone augmented the hepatotoxicity of chloroform, 1,1,2-trichloroethane and trichloroethylene. The most marked potentiation was seen with chloroform. There was no augmentation of hepatic dysfunction with 1,1,1-trichloroethane. The study indicates that the ability of isopropyl alcohol or acetone to potentiate the hepatotoxicity of chlorinated hydrocarbons is proportional to the basic hepatotoxicity of the solvent involved. |
Descriptores (primarios) |
acetona; alcohol isopropílico; sinergismo; hidrocarburos clorados; toxicología |
Descriptores (secundarios) |
efectos hepatotóxicos; cloroformo; tricloro-1,1,2 etano; investigaciones en el animal; tricloroetileno |
Tipo de documento |
- |
Tema(s) |
Sustancias tóxicas y peligrosas
|
Broad subject area(s) |
|
Navegación por categoria(s) |
Alcohols Ketones Halogenated hydrocarbons
|