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Base de datos CISDOC

ID (ISN) del documento21858
Número CIS 74-1926
ISSN - Título de la serie 0003-9896 - Archives of Environmental Health
Año 1974
Número de serie
Autor(es) Traiger G.J., Plaa G.L.
Título Chlorinated hydrocarbon toxicity - Potentiation by isopropyl alcohol and acetone.
Información bibliográfica May 1974, Vol.28, No.5, p.276-278. 10 ref.
Resumen In experiments with mice it was shown that pre-treatment with isopropyl alcohol or acetone augmented the hepatotoxicity of chloroform, 1,1,2-trichloroethane and trichloroethylene. The most marked potentiation was seen with chloroform. There was no augmentation of hepatic dysfunction with 1,1,1-trichloroethane. The study indicates that the ability of isopropyl alcohol or acetone to potentiate the hepatotoxicity of chlorinated hydrocarbons is proportional to the basic hepatotoxicity of the solvent involved.
Descriptores (primarios) acetona; alcohol isopropílico; sinergismo; hidrocarburos clorados; toxicología
Descriptores (secundarios) efectos hepatotóxicos; cloroformo; tricloro-1,1,2 etano; investigaciones en el animal; tricloroetileno
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Alcohols
Ketones
Halogenated hydrocarbons