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Base de datos CISDOC

ID (ISN) del documento21223
Número CIS 74-1313
ISSN - Título de la serie 0004-1254 - Arhiv za higijenu rada i toksikologiju
Año 1973
Número de serie
Autor(es) Pleština R., Svetličić B.
Título Toxic effects of two carbamate insecticides in dogs.
Información bibliográfica 1973, Vol.24, No.3, p.217-225. Illus. 19 ref.
Resumen The authors observed a difference in duration of plasma cholinesterase inhibition in workers exposed to propoxur (2-isopropoxyphenyl methylcarbamate) and promecarb (3-methyl-5-isopropylphenyl-N-methylcarbamate). To find out whether this difference is due to the enzyme-inhibitor interaction or to differences in absorption, they administered equitoxic doses of the 2 carbamates to dogs by intravenous and intramuscular injections. While a difference in inhibition duration was found only after intramuscular injection, the enzyme activity recovery was similar for both carbamates after intravenous injection. The delayed plasma cholinesterase recovery after promecarb administration was due to the much slower absorption of the compound after intramuscular injection.
Descriptores (primarios) carbamatos; toxicología; insecticidas; alteraciones enzimáticas
Descriptores (secundarios) metabolización; investigaciones en el animal; promecarbamatos; arprocarbamatos
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Agricultural chemicals
Blood diseases
Amides