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Base de datos CISDOC

ID (ISN) del documento20834
Número CIS 74-674
ISSN - Título de la serie 0013-9351 - Environmental Research
Año 1973
Número de serie
Autor(es) Zaidi S.H., Dogra R.K.S., Shanker R., Chandra S.V.
Título Experimental infective manganese pneumoconiosis in guinea pigs.
Información bibliográfica Sep. 1973, Vol.6, No.3, p.287-297. Illus. 30 ref.
Resumen To assess the role of an infective factor in the production of manganese pneumoconiosis, guinea pigs were intratracheally inoculated with only Candida ablicans (a facultative pathogen of the upper respiratory tract), only manganese dioxide or a combination of both. Histopathological studies revealed at the termination of the experiments (180 days) that the dust and organism together produced thick reticulin and collagen fibrosis in the lungs; manganese dioxide alone produced a fibrotic reaction comprised of only thick reticulin fibres, while the organism alone produced slight lymphoid hyperplasia and no fibrosis.
Descriptores (primarios) dióxido de manganeso; cándida albicans; neumoconiosis del manganeso; polvos; enfermedades infecciosas
Descriptores (secundarios) desarrollo del tejido conjuntivo; histopatología; investigaciones en el animal
Tipo de documento -
Tema(s) Polvos, aerosoles
Broad subject area(s)
Navegación por categoria(s) Neumoconiosis
Inorganic substances
Bacterial and parasitic diseases