| ID (ISN) del documento | 18790 |
| Número CIS |
73-1135 |
| ISSN - Título de la serie |
0003-9896 - Archives of Environmental Health |
| Año |
1972 |
| Número de serie |
|
| Autor(es) |
Stokinger H.E. |
| Título |
Concepts of thresholds in standards setting |
| Información bibliográfica |
Sep. 1972, Vol.25, No.3, p.153-157. Illus. 5 ref. |
| Resumen |
A discussion of the premises on which the concept of threshold of toxicological response is based, confined to chemical substances in the air of workplaces, for which the threshold concept is represented by a non-linear relationship between dose and initial response. The metabolic factors governing toxicological response - particularly homeostasis and adaptation, are reviewed. The precautions to be observed in establishing threshold limit values for man in industry are discussed at some length (heterogeneity of the human species, synergistic factors - alcohol drinking, smoking, dietary habits, predisposing diseases, etc.). |
| Descriptores (primarios) |
valores umbrales; determinación de la concentración; substancias tóxicas; toxicología |
| Descriptores (secundarios) |
efectos tóxicos; polvos en suspensión aérea; metabolización; alcoholismo; relación dosis-respuesta; substancias nocivas; régimen alimenticio; sinergismo; dosis absorbida; fumadores |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Nutrición
Occupational exposure limits
Abuso de alcohol y drogas
|
