| ID (ISN) del documento | 18744 |
| Número CIS |
73-1379 |
| ISSN - Título de la serie |
0002-8894 - American Industrial Hygiene Association Journal |
| Año |
1972 |
| Número de serie |
|
| Autor(es) |
Mullin L.S. |
| Título |
Halogenated hydrocarbon-induced cardiac arrhythmias associated with release of endogenous epinephrine |
| Información bibliográfica |
June 1972, Vol.33, No.6, p.389-396. Illus. 23 ref. |
| Resumen |
Certain unsubstituted and halogenated hydrocarbons are known to release endogenous epinephrine and to cause cardiac sensitisation. Experiments were carried out on exercising dogs exposed to known concentrations of flurocarbons 11, 12 and 114; exercise was chosen as a means of increasing the production of epinephrine to a level where cardiac sensitisation could occur. It was found that, whereas fluorocarbons 12 and 114 did produce cardiac sensitisation, a much higher concentration was needed to produce this effect than with intravenous epinephrine administration. Fluorocarbon 11 did not produce the same effect at the test concentrations chosen. |
| Descriptores (primarios) |
hidrocarburos heterohalogenados; riesgos biológicos; excreción de adrenalina; arritmia |
| Descriptores (secundarios) |
diclorotetrafluoroetano; diclorodifluorometano; triclorofluorometano; trastornos funcionales cardiacos; exposición; trastornos suprarrenales; investigaciones en el animal; efectos biológicos; inhalación |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Halogenated hydrocarbons
Biological hazards
Cardiovascular diseases
|
