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Base de datos CISDOC

ID (ISN) del documento112086
Número CIS 11-0675
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 2011
Número de serie
Autor(es) Boffetta P., Fontana L., Stewart P., Zaridze D., Szeszenia-Dabrowska N., Janout V., Bencko V., Foretova L., Jinga V., Matveev V., Kollarova H., Ferro G., Chow W.H., Rothman N., van Bemmel D., Karami S., Brennan P., Moore L.E.
Título Occupational exposure to arsenic, cadmium, chromium, lead and nickel, and renal cell carcinoma: A case-control study from Central and Eastern Europe
Información bibliográfica Oct. 2011, Vol.68, No.10, p.723-728. 37 ref.
Resumen The objective of this study was to investigate the risk of renal cell carcinoma (RCC) in Central and Eastern Europe in relation to exposure to known and suspected carcinogenic metals. During 1999-2003, a hospital-based study was conducted in the Czech Republic, Poland, Romania and Russia, including 1097 cases of RCC and 1476 controls. Occupational exposure to arsenic, cadmium, chromium, lead and nickel was assessed by teams of local industrial hygiene experts, based on detailed occupational questionnaires. The odds ratios (ORs) for RCC were 1.55 for exposure to lead and 1.40 for exposure to cadmium. No clear monotonic exposure-response relation was apparent for either duration of exposure or cumulative exposure to either metal, although the OR for the highest category of cumulative exposure to lead was 2.25. Exposure to other metals did not entail an increased risk of RCC.
Descriptores (primarios) cromo y sus compuestos; níquel y sus compuestos; arsénico y sus compuestos; cadmio y sus compuestos; plomo y sus compuestos; cáncer renal; factores de riesgo
Descriptores (secundarios) República Checa; Polonia; Rumania; Federación de Rusia; valoración de la exposición; encuesta por cuestionario; estudio del caso y testigo; valoración estadística; relación trabajo-exposición
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Sustancias tóxicas y peligrosas
Broad subject area(s) Medicina del trabajo, epidemiología
Riesgos químicos
Navegación por categoria(s) Cancer and carcinogens
Cadmium and compounds
Arsenic and compounds
Lead and compounds
Nickel and compounds