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Base de datos CISDOC

ID (ISN) del documento111958
Número CIS 11-0682
ISSN - Título de la serie 0019-8366 - Industrial Health
Año 2010
Número de serie
Autor(es) Sellappa S., Sadhanandhan B., Francis A., Vasudevan S.G.
Título Evaluation of genotoxicity in petrol station workers in South India using micronucleus assay
Información bibliográfica Nov. 2010, Vol.48, No.6, p.852-856. 32 ref.
Acceso Internet Evaluation_of_genotoxicity.pdf [en inglés]
Resumen In this study, the micronucleus (MN) frequency was assessed as a measure of genotoxicity in exfoliated cells of buccal mucosa extracted from 110 service station attendants and 100 controls. For each individual, 3000 exfoliated buccal cells were analyzed. The individuals used in the study were grouped based on their smoking, drinking alcoholic beverages, and tobacco chewing habits. After controlling for smoking, alcohol consumption, age and length of occupation, there was a significantly higher frequency of micronucleated cells among the workers exposed to gasoline than in the unexposed control population. The significant increase in the induction of the MN in the exposed population suggests that the studied individuals may be at a higher risk of developing cancer and therefore should be monitored for possible long-term adverse effects of the exposure.
Descriptores (primarios) India; combustible de motor; estaciones de servicio; anomalías genéticas; toxicidad por inhalación; factores de riesgo
Descriptores (secundarios) dosificación en los tejidos; patología experimental; estudio del caso y testigo; valoración estadística
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Sustancias tóxicas y peligrosas
Cemercio, servicios, oficinas
Broad subject area(s) Riesgos químicos
Medicina del trabajo, epidemiología
Navegación por categoria(s) Risk evaluation
Toxicology
Petroleum and natural gas industry