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Base de datos CISDOC

ID (ISN) del documento111912
Número CIS 11-0513
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 2009
Número de serie
Autor(es) MacCarthy A., Bunch K.J., Fear N.T, King J.C., Vincent T.J., Murphy M.F.
Título Paternal occupation and retinoblastoma: A case-control study based on data for Great Britain 1962-1999
Información bibliográfica Oct. 2009, Vol.66, No.10, p.644-649. 22 ref.
Resumen The objective of this study was to examine the association between paternal occupational exposures and retinoblastoma using birth registration data for cases from the National Registry of Childhood Tumours (NRCT) and controls from the general population of Great Britain. It was conducted in the form of a case-control study of paternal occupational data for 1318 cases of retinoblastoma, born and diagnosed between 1962 and 1999, and 1318 controls matched on sex, date of birth and birth registration sub-district. Paternal occupations at birth were grouped according to inferred exposure using an occupational exposure classification scheme. A conditional (matched) case-control analysis was used to estimate odds ratios (ORs) for each paternal occupational exposure group. For non-heritable retinoblastoma, a statistically significant increased risk was found with father's definite occupational exposure to oil mists in metal working (OR 1.85). No statistically significant associations were observed for other exposure groups.
Descriptores (primarios) cáncer; lesiones retinianas; ninos; exposición de los padres; factores de riesgo
Descriptores (secundarios) niebla de aceite; líquidos de corte; estudio del caso y testigo; transformación de metales
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Sustancias tóxicas y peligrosas
Broad subject area(s) Medicina del trabajo, epidemiología
Riesgos químicos
Navegación por categoria(s) Cancer and carcinogens
Risk evaluation
Metalworking industry