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ID (ISN) del documento111899
Número CIS 11-0506
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 2010
Número de serie
Autor(es) Heck J.E., Charbotel B., Moore L.E., Karami S., Zaridze D.G., Matveev V., Janout V., Kollárová H., Foretova L., Bencko V., Szeszenia-Dabrowska N., Lissowska J., Mates D., Ferro G., Chow W.H., Rothman N., Stewart P., Brennan P., Boffetta P.
Título Occupation and renal cell cancer in Central and Eastern Europe
Información bibliográfica Jan. 2010, vol.67, No.1, p.47-53. 42 ref.
Resumen Central and Eastern Europe has among the highest rates of renal cell cancer worldwide. Few studies have been conducted in these areas to investigate the possible role of occupational exposures in renal cell cancer aetiology. The purpose of this study was to examine the association of renal cell cancer with employment in specific occupations and industries. From 1999 to 2003, a hospital-based case-control study was conducted in seven areas of the Czech Republic, Poland, Romania and Russia. A detailed occupational history was collected from renal cell cancer cases and controls, together with information on potential confounders. Odds ratios (ORs) of cancer risk were calculated for having ever been employed in selected jobs and industries, with follow-up analyses examining duration of employment. A total of 992 histologically-confirmed incident renal cell cancer cases and 1459 controls were included in the analysis. An increased risk of renal cell cancer was observed for workers in agricultural labour and animal husbandry (OR 1.43), particularly among women employed as general farm workers (OR 2.73). Risk gradients for agricultural work increased with longer employment. An overall increased risk of renal cell cancer was seen among architects and engineers (OR 1.89), and mechanical engineers (OR 1.71).
Descriptores (primarios) Europa Oriental; epidemiología; relación entre la profesión y la enfermedad; cáncer renal; relación trabajo-exposición; factores de riesgo
Descriptores (secundarios) República Checa; Polonia; Rumania; Federación de Rusia; diagnostico; antigüedad; histopatología; estudio del caso y testigo; valoración estadística; duración de la exposición
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s) Medicina del trabajo, epidemiología
Navegación por categoria(s) Cancer and carcinogens
Diseases of the kidney and the urinary system