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Base de datos CISDOC

ID (ISN) del documento110768
Número CIS 10-0342
ISSN - Título de la serie 0355-3140 - Scandinavian Journal of Work, Environment and Health
Año 2010
Número de serie
Título Occupational rhinosinusitis due to etoposide, an antineoplastic agent
Información bibliográfica May 2010, Vol.36, No.3, p.266-267. 7 ref.
Acceso Internet 10-0342.pdf [en inglés]
Resumen This article reports a rare case of an occupational hypersensitivity reaction to an antineoplastic agent in a 45-year-old nurse who developed throat irritation and chronic nasal congestion followed by sinusitis shortly after beginning work at an oncological out-patient clinic. The symptoms disappeared upon leaving the clinic two years later, but they returned when she resumed work at the oncology unit of a hospital in Denmark, handling chemotherapy on a daily basis. In vitro histamine release tests were performed against nine suspected antineoplastic agents. The patient's histamine release test against the antineoplastic agent etoposide was positive; the other test results were negative. The histamine release test against etoposide using passive sensitization was also negative. Upon leaving the oncology department, the symptoms of the nurse disappeared once again. She was given a diagnosis of rhinosinusitis.
Descriptores (primarios) médicamentos anticancerosos; rinitis; sinusitis; personal de enfermería
Descriptores (secundarios) Dinamarca; sensibilización; síntomas; liberación de histamina; pruebas in vitro; cambios de puestos de trabajo; hospitales; estudio de caso
Tipo de documento D - Artículos periódicos
Tema(s) Cemercio, servicios, oficinas
Broad subject area(s) Medicina del trabajo, epidemiología
Navegación por categoria(s) Ionizing radiation
Health care services