| ID (ISN) del documento | 110269 |
| Número CIS |
09-1234 |
| ISSN - Título de la serie |
0340-0131 - International Archives of Occupational and Environmental Health |
| Año |
2009 |
| Número de serie |
|
| Autor(es) |
Taeger D., Johnen G., Wiethege T., Tapio S., Möhner M., Wesch H., Tannapfel A., Müller K.M., Brüning T., Pesch B. |
| Título |
Major histopathological patterns of lung cancer related to arsenic exposure in German uranium miners |
| Información bibliográfica |
July 2009, Vol.82, No.7, p.867-875. Illus. 45 ref. |
| Resumen |
A comprehensive histopathological database and a detailed job-exposure matrix developed for former German uranium miners with exposure to arsenic, radon, and quartz were analyzed to quantitatively assess the effect of arsenic regarding cell type of lung cancer. An arsenic-related increase of the proportion of squamous cell carcinoma of the lung was observed, but was restricted to miners without silicosis. The increase was found at all levels of co-exposure to radon and quartz dust. In miners with silicosis, the proportion of adenocarcinoma increased with rising arsenic exposure. Other findings are discussed. |
| Descriptores (primarios) |
Alemania; minas de uranio; histopatología; cáncer de pulmón |
| Descriptores (secundarios) |
radón; arsénico y sus compuestos; cuarzo; bases de datos automatizadas; factores de confusión; relación trabajo-exposición; silicosis |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Alemania |
| Tema(s) |
Minas y canteras
|
| Broad subject area(s) |
Riesgos químicos
Medicina del trabajo, epidemiología
|
| Navegación por categoria(s) |
Mining and quarrying
Radon
Diseases of the respiratory system (except for pneumoconiosis & similar)
|
