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ID (ISN) del documento110238
Número CIS 09-1304
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 2009
Número de serie
Autor(es) Garlantézec R., Monfort C., Rouget F., Cordier S.
Título Maternal occupational exposure to solvents and congenital malformations: A prospective study in the general population
Información bibliográfica July 2009, Vol.66, No.7, p.456-463. 40 ref.
Resumen To study the relations between maternal occupational exposure to solvents during pregnancy and the risk of congenital malformations, a prospective population-based cohort study was undertaken in three districts of Brittany, France, involving 3421 pregnant women. Occupational exposure to solvents at the beginning of pregnancy was assessed from the women's self-reported occupational exposures and from a job-exposure matrix. Logistic regressions were used to adjust for potential confounders. Significant associations were found between major congenital malformations and maternal occupational exposure to solvents by both self-reports and the job-exposure matrix (OR 2.48 and 3.48 respectively for the highest and lowest exposure groups). A significant dose-response trend was observed with both exposure assessment methods. Other findings are discussed.
Descriptores (primarios) Francia; disolvente; embarazadas; factores de riesgo; efectos teratogénicos
Descriptores (secundarios) apreciación subjetiva; exposición de los padres; valoración de la exposición; valoración estadística; relación dosis-respuesta; relación trabajo-exposición; estudio de cohorte
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaFrancia
Tema(s) Patología profesional
Broad subject area(s) Riesgos químicos
Medicina del trabajo, epidemiología
Navegación por categoria(s) Genetic factors in reaction to exposures
Antifertility and prenatal effects