ID (ISN) del documento | 110238 |
Número CIS |
09-1304 |
ISSN - Título de la serie |
1351-0711 - Occupational and Environmental Medicine |
Año |
2009 |
Número de serie |
|
Autor(es) |
Garlantézec R., Monfort C., Rouget F., Cordier S. |
Título |
Maternal occupational exposure to solvents and congenital malformations: A prospective study in the general population |
Información bibliográfica |
July 2009, Vol.66, No.7, p.456-463. 40 ref. |
Resumen |
To study the relations between maternal occupational exposure to solvents during pregnancy and the risk of congenital malformations, a prospective population-based cohort study was undertaken in three districts of Brittany, France, involving 3421 pregnant women. Occupational exposure to solvents at the beginning of pregnancy was assessed from the women's self-reported occupational exposures and from a job-exposure matrix. Logistic regressions were used to adjust for potential confounders. Significant associations were found between major congenital malformations and maternal occupational exposure to solvents by both self-reports and the job-exposure matrix (OR 2.48 and 3.48 respectively for the highest and lowest exposure groups). A significant dose-response trend was observed with both exposure assessment methods. Other findings are discussed. |
Descriptores (primarios) |
Francia; disolvente; embarazadas; factores de riesgo; efectos teratogénicos |
Descriptores (secundarios) |
apreciación subjetiva; exposición de los padres; valoración de la exposición; valoración estadística; relación dosis-respuesta; relación trabajo-exposición; estudio de cohorte |
Tipo de documento |
D - Artículos periódicos |
País / Estado o Provincia | Francia |
Tema(s) |
Patología profesional
|
Broad subject area(s) |
Riesgos químicos Medicina del trabajo, epidemiología
|
Navegación por categoria(s) |
Genetic factors in reaction to exposures Antifertility and prenatal effects
|