| ID (ISN) del documento | 109743 |
| Número CIS |
09-645 |
| ISSN - Título de la serie |
0271-3586 - American Journal of Industrial Medicine |
| Año |
2008 |
| Número de serie |
|
| Autor(es) |
Wu F., Xia Z., Qu Y., Tang Y., Cao D., Sun P., Christiani D.C. |
| Título |
Genetic polymorphisms of IL-1A, IL-1B, IL-1RN, NFKB1, FAS, and FASL, and risk of silicosis in a Chinese occupational population |
| Información bibliográfica |
Nov. 2008, Vol.51, No.11, p.843-851. 26 ref. |
| Resumen |
To test whether polymorphisms in IL-1, NF-KB, FAS and FASL genes are associated with risk of silicosis, a case-control study was conducted with 183 silicosis patients and 111 silica-exposed miners who were frequency-matched by age, dust exposure duration, work location, and type of work. Genotype analysis was performed on genomic DNA, using a PCR-RFLP assay. Findings are discussed. |
| Descriptores (primarios) |
China; silicosis; minas; factores de riesgo; efectos genéticos |
| Descriptores (secundarios) |
ADN; estudio del caso y testigo; sílice |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | China; Estados Unidos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Mining and quarrying
Genetic factors in reaction to exposures
Neumoconiosis
Antifertility and prenatal effects
|
