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ID (ISN) del documento109743
Número CIS 09-645
ISSN - Título de la serie 0271-3586 - American Journal of Industrial Medicine
Año 2008
Número de serie
Autor(es) Wu F., Xia Z., Qu Y., Tang Y., Cao D., Sun P., Christiani D.C.
Título Genetic polymorphisms of IL-1A, IL-1B, IL-1RN, NFKB1, FAS, and FASL, and risk of silicosis in a Chinese occupational population
Información bibliográfica Nov. 2008, Vol.51, No.11, p.843-851. 26 ref.
Resumen To test whether polymorphisms in IL-1, NF-KB, FAS and FASL genes are associated with risk of silicosis, a case-control study was conducted with 183 silicosis patients and 111 silica-exposed miners who were frequency-matched by age, dust exposure duration, work location, and type of work. Genotype analysis was performed on genomic DNA, using a PCR-RFLP assay. Findings are discussed.
Descriptores (primarios) China; silicosis; minas; factores de riesgo; efectos genéticos
Descriptores (secundarios) ADN; estudio del caso y testigo; sílice
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaChina; Estados Unidos
Tema(s) Patología profesional
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Antifertility and prenatal effects
Mining and quarrying
Genetic factors in reaction to exposures
Neumoconiosis