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Base de datos CISDOC

ID (ISN) del documento109497
Número CIS 09-404
ISSN - Título de la serie 1059-924X - Journal of Agromedicine
Año 2008
Número de serie
Autor(es) McCauley L.A., Lasarev M., Muniz J., Nazar Stewart V., Kisby G.
Título Analysis of pesticide exposure and DNA damage in immigrant farmworkers
Información bibliográfica 2008, Vol.13, No.4, p.237-246. Illus. 33 ref.
Resumen This study was designed to use the comet assay to describe the association of markers of DNA damage in oral leukocytes with biomarkers of pesticide exposure. It involved 134 farmworkers working in berry crops in the U.S. State of Oregon and 55 non exposed controls. It also examined the extent of DNA damage in young workers compared to adults and the effect of work histories, lifestyle factors, and diet on markers of DNA damage. Tail intensity and tail moment were significantly higher for agricultural workers compared to controls. However no parameter was significantly associated with years spent working in agriculture, age, sex, body mass index, diet, and alcohol or tobacco use. The results of this study demonstrate the feasibility for using the comet assay in biomonitoring studies of farmworkers.
Descriptores (primarios) leucocitos; Oregón; compuestos organofosforados; agricultura; pesticidas; insecticidas; ADN
Descriptores (secundarios) captano; Estados Unidos; fiabilidad; dosificación en la orina; estudio del caso y testigo; descripción del procedimiento; encuesta por cuestionario
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaEstados Unidos
Tema(s) Agricultura, pesca, cría de ganado
Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Agricultura
Agricultural chemicals