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ID (ISN) del documento109373
Número CIS 09-323
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 2009
Número de serie
Autor(es) van Rooy F.G.B.G.J., Smit L.A.M., Houba R., Zaat V.A.C., Rooyackers J.M., Heederik D.J.
Título A cross-sectional study of lung function and respiratory symptoms among chemical workers producing diacetyl for food flavourings
Información bibliográfica Feb. 2009, Vol.66, No.2, p.105-110. Illus. 16 ref.
Resumen Four workers of a diacetyl (also known as 2,3-butanedione) plant in the Netherlands were diagnosed with a bronchiolitis obliterans syndrome. This lead to an investigation of exposures, respiratory symptoms, lung function and exposure-response relationships in a cohort of 175 workers having worked at the plant between 1960 and 2003. Lung function and questionnaire data on respiratory symptoms were compared to a general population sample and to an unexposed internal reference group. Compared to the two reference groups, diacetyl exposed workers reported significantly more respiratory symptoms, daily cough and asthma. A relationship between exposure and FEV1 was also observed. The excess of respiratory symptoms in this retrospective cohort suggests that diacetyl production poses an occupational hazard.
Descriptores (primarios) industria química; cetonas; factores de riesgo; enfermedades respiratorias; aditivos alimentarios; butanodione-2,3
Descriptores (secundarios) Países Bajos; síntomas; disnea; asma; pruebas funcionales respiratorias; encuesta por cuestionario; estudio de cohorte; estudio transversal; volumen espiratorio máximo por segundo
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaPaíses Bajos
Tema(s) Química, hidrocarburos,plásticos, caucho
Broad subject area(s) Riesgos químicos
Medicina del trabajo, epidemiología
Navegación por categoria(s) Diseases of the respiratory system (except for pneumoconiosis & similar)
Ketones
Chemical industry