| ID (ISN) del documento | 109298 |
| Número CIS |
09-393 |
| ISSN - Título de la serie |
1351-0711 - Occupational and Environmental Medicine |
| Año |
2008 |
| Número de serie |
|
| Autor(es) |
Sikkeland L.I.B., Skogstad M., Øvstebø R., Brusletto B., Haug K.B.F., Kongerud J., Eduard W., Kierulf P. |
| Título |
Circulating lipopolysaccharides in the blood from "bioprotein" production workers |
| Información bibliográfica |
Mar. 2008, Vol.65, No.3, p.211-214. Illus. 13 ref. |
| Resumen |
Workers producing bacterial single-cell protein (bioprotein) are exposed to organic dust containing high levels of endoxins (lipopolysaccharides, LPS). Workers in this industry have complained of episodes of fever, fatigue, chest tightness, skin dryness and rubor. The aim of this study was to quantify LPS and inflammatory mediators in plasma in eight non-smoking production and eight non-smoking, non-exposed controls. Airborne and plasma endotoxin concentrations were measured, as well as plasma high sensitivity C-reactive protein and different cytokines, chemokines and metalloproteinases. The workers who did not use personal respiratory protection were exposed to varying airborne levels of endotoxin (75-15,000 EU/m3). The level of plasma LPS was significantly elevated among the workers compared to the non-exposed controls. The workers also had increased levels of several inflammatory cytokines. |
| Descriptores (primarios) |
toxinas bacterianas; riesgos biológicos; valoración de la exposición; inhalación |
| Descriptores (secundarios) |
proteínas; polisacáridos; interleucinas; dosificación en la sangre; respiradores; dosificación en el aire; estudio del caso y testigo |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Noruega |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos biológicos
Riesgos químicos
|
| Navegación por categoria(s) |
Biological hazards
Exposure evaluation
|
