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ID (ISN) del documento109100
Número CIS 09-127
ISSN - Título de la serie 0019-8366 - Industrial Health
Año 2008
Número de serie
Autor(es) Ohbayashi H., Saito M., Senoh H., Umeda Y., Aiso S., Yamazaki K., Nagano K., Yamamoto S., Fukushima S.
Título Occurrence of two different types of glutathione S-transferase placental form-positive hepatocytes after a single administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats
Información bibliográfica May 2008, Vol.46, No.3, p.281-288. Illus. 40 ref.
Resumen Occurrence of glutathione S-transferase placental form (GST-P)-positive hepatocytes was examined, using 15 Wistar rats of both sexes each orally administered 2,3,7,8-tetrabromo-dibenzo-p-dioxin (TBDD) by gavage at a single dose of 0, 10, 30, 100 or 300 µ/kg body weight. Liver tissues were stained with anti-GST-P antibody. The characteristics of the two types of GST-P-positive hepatocytes which were found in the TBDD-dosed rat are discussed.
Descriptores (primarios) hígado; glutation-transferasa; tetrabromodibenzodioxina
Descriptores (secundarios) anticuerpos; microscopía; investigaciones en el animal
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaJapón
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Heterocyclic compounds