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ID (ISN) del documento109060
Número CIS 09-165
ISBN(s) 978-92-4-156360-4
Año 2008
Número de serie Harmonization Project Document No.5
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
Título Skin sensitization in chemical risk assessment
Información bibliográfica World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2008. iv, 85p. Illus. Bibl.ref.
Acceso Internet [en inglés]
Resumen This harmonization project activity in 2006 focused on skin sensitization in chemical risk assessment. An IPCS international workshop was convened from 17-18 October 2006, in Berlin, Germany with the aim of evaluating experimental techniques for their ability to produce data to inform risk assessment, including provision of dose-response information and information relating to sensitive sub-populations. The workshop focused on whether it is possible to distinguish between chemicals with a high potency to elicit allergic skin reactions and those with a low potency. Emerging approaches, such as structure activity relationships (SAR), were explored. The meeting also explored whether assessment approaches for skin sensitization could inform approaches for the respiratory tract.
Descriptores (primarios) OMS; alergias cutáneas; tests cutáneos; productos químicos; valoración del riesgo; sensibilizadores
Descriptores (secundarios) alergenos; PISSC; sensibilización; relación dosis-respuesta; conferencia; fiabilidad
Tipo de documento E - Libros, informes, actas
País / Estado o ProvinciaOMS
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Skin diseases
Risk evaluation