ID (ISN) del documento | 108529 |
Número CIS |
08-1070 |
ISSN - Título de la serie |
1076-2752 - Journal of Occupational and Environmental Medicine |
Año |
2007 |
Número de serie |
|
Autor(es) |
Sikkeland L.I.B., Haug T., Stangeland A.M., Flatberg G., Søstrand P., Halvorsen B, Kongerud J. |
Título |
Airway inflammation in paper mill workers |
Información bibliográfica |
Oct. 2007, Vol.49, No.10, p.1135-1142. Illus. 24 ref. |
Resumen |
Paper mill workers are exposed to microorganisms. To study whether inflammatory airway response could be detected in sputum of non-symptomatic workers, 29 healthy nonsmoking men were recruited from four paper mills in Norway; 17 were exposed to high levels of and 12 workers to low levels of microorganisms. A reference group of 22 healthy, nonsmoking, non-exposed men was also studied. Differential cell counts of induced sputum were performed, gene expressions of isolated sputum macrophages were studied and inflammatory parameters were analyzed. Sputum from highly-exposed workers had a significantly higher percentage of neutrophils than that from low-exposed and non-exposed workers. There was also an increased gene expression of various inflammatory parameters in induced sputum from the highly-exposed group. These findings show that paper industry workers exposed to microorganisms develop sub-clinical airway inflammation. |
Descriptores (primarios) |
Noruega; microrganismos; tests de exposición; fabricación de papel y cartón; expectoración |
Descriptores (secundarios) |
macrófagos; trabajadores masculinos; síntomas; citología del esputo; valoración de la exposición; estudio del caso y testigo; enfermedades respiratorias |
Tipo de documento |
D - Artículos periódicos |
País / Estado o Provincia | Noruega |
Tema(s) |
Papel, artes gráficas
|
Broad subject area(s) |
Medicina del trabajo, epidemiología Riesgos biológicos Industrias y ocupaciones
|
Navegación por categoria(s) |
Paper and paper products industry Biological monitoring Diseases of the respiratory system (except for pneumoconiosis & similar)
|