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Base de datos CISDOC

ID (ISN) del documento108529
Número CIS 08-1070
ISSN - Título de la serie 1076-2752 - Journal of Occupational and Environmental Medicine
Año 2007
Número de serie
Autor(es) Sikkeland L.I.B., Haug T., Stangeland A.M., Flatberg G., Søstrand P., Halvorsen B, Kongerud J.
Título Airway inflammation in paper mill workers
Información bibliográfica Oct. 2007, Vol.49, No.10, p.1135-1142. Illus. 24 ref.
Resumen Paper mill workers are exposed to microorganisms. To study whether inflammatory airway response could be detected in sputum of non-symptomatic workers, 29 healthy nonsmoking men were recruited from four paper mills in Norway; 17 were exposed to high levels of and 12 workers to low levels of microorganisms. A reference group of 22 healthy, nonsmoking, non-exposed men was also studied. Differential cell counts of induced sputum were performed, gene expressions of isolated sputum macrophages were studied and inflammatory parameters were analyzed. Sputum from highly-exposed workers had a significantly higher percentage of neutrophils than that from low-exposed and non-exposed workers. There was also an increased gene expression of various inflammatory parameters in induced sputum from the highly-exposed group. These findings show that paper industry workers exposed to microorganisms develop sub-clinical airway inflammation.
Descriptores (primarios) Noruega; microrganismos; tests de exposición; fabricación de papel y cartón; expectoración
Descriptores (secundarios) macrófagos; trabajadores masculinos; síntomas; citología del esputo; valoración de la exposición; estudio del caso y testigo; enfermedades respiratorias
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaNoruega
Tema(s) Papel, artes gráficas
Broad subject area(s) Medicina del trabajo, epidemiología
Riesgos biológicos
Industrias y ocupaciones
Navegación por categoria(s) Paper and paper products industry
Biological monitoring
Diseases of the respiratory system (except for pneumoconiosis & similar)