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Document ID (ISN)78736
CIS number 02-944
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2002
Convention or series no.
Author(s) Garb J.R.
Title One-year study of occupational human immunodeficiency virus postexposure prophylaxis
Bibliographic information Mar. 2002, Vol.44, No.3, p.265-270. 14 ref.
Abstract A 12-month experience with human immunodeficiency virus (HIV) post-exposure prophylaxis (PEP) in a specialized medical care centre in the United States was evaluated for timeliness of treatment and adherence to treatment recommendations. 46 health care workers were started on HIV PEP. Risk status of the source patient, rather than type of exposure, was a significant determinant for both initiating and completing treatment. Of those exposed to HIV-positive sources, 79% completed the full 28 days of therapy. Only 22% of all health care workers who started PEP discontinued treatment because of adverse effects. The mean time from exposure to first dose of PEP was one hour and 46 minutes. The use of a defined treatment protocol, with supporting educational material and immediately-available PEP medication is an effective way of managing HIV exposures.
Descriptors (primary) occupational diseases; immunodeficiency syndrome; prophylaxis; biological hazards; health care personnel
Descriptors (secondary) pharmacological prevention; hospitals; programme evaluation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Commerce, services, offices
Broad subject area(s) Biological hazards
Browse category(ies) HIV/AIDS
Health care services
Biological hazards