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Document ID (ISN)78721
CIS number 02-666
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2002
Convention or series no.
Author(s) Schliemann-Willers S., Wigger-Alberti W., Kleesz P., Grieshaber R., Elsner P.
Title Natural vegetable fats in the prevention of irritant contact dermatitis
Bibliographic information Jan. 2002, Vol.46, No.1, p.6-12. Illus. 30 ref.
Abstract Chronic irritant contact dermatitis (ICD) is common in the food processing industry. To date, protective creams that comply with the special requirements in the food industry have not been available. This study evaluates the efficacy of pre-exposure application of natural vegetable fats in the prevention of experimentally-induced ICD. Twenty healthy volunteers were subjected to a repetitive irritation test using sodium lauryl sulfate. The application area was the paravertebral skin of mid back. Clinical assessment and bioengineering measurements were carried out one day before and five days after the application of the test substances. Rape seed and palm fats showed significant protective potential. Higher content of linoleic acid and lower content of oleic acid was associated with beneficial effects. The results show promise for the prevention of ICD and towards the development of new protective preparations for workplaces in the foodstuffs industry.
Descriptors (primary) irritants; skin creams; food industry; dermatitis; vegetable oils and fats
Descriptors (secondary) long-chain fatty acids; skin tests; oleic acid; sodium dodecylsulfate
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Food industry
Skin diseases