|Document ID (ISN)||78714|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Cocco P., Rice C.H., Chen J.Q., McCawley M.A., McLaughlin J.K., Dosemeci M.
||Lung cancer risk, silica exposure, and silicosis in Chinese mines and pottery factories: The modifying role of other workplace lung carcinogens
||Dec. 2001, Vol.40, No.6, p.674-682. 32 ref.
||02-0846.pdf [in English]
||To explore whether exposure to other lung carcinogens, or clinical features of silicosis, modify or confound the association between silica and lung cancer, data from a nested case-control study conducted in the late 1980s in 29 Chinese mines and potteries were used. The were 316 lung cancer cases and 1,356 controls, matched by decade of birth and facility type. Pooling the 29 work sites, the study showed a moderate association between lung cancer risk and silica exposure. Risk did not vary after excluding subjects with silicosis or adjusting the risk estimates by radiological staging of silicosis. The results suggest that numerous occupational and non-occupational risk factors interact in a complex fashion to modify lung cancer risk.
||carcinogens; silica; lung cancer; mining industry; confounding factors; risk factors; pottery
||China; non-occupational factors; case-control study; silicosis; radiological diagnosis
||D - Periodical articles
|Country / State or Province||China; Italy; USA|
||Materials, glass and ceramics
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)
Mining and quarrying