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CISDOC database

Document ID (ISN)78665
CIS number 02-577
ISBN(s) 92-4-153039-1
Year 2002
Convention or series no. CICAD No.39
Author(s)
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
Title Acrylonitrile
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2002. iv, 51p. Illus. Approx. 220 ref.
Internet access http://www.who.int/ipcs/publications/cicad/en/cicad39.pdf [in English]
Abstract Conclusions of this criteria document on acrylonitrile: data from animal studies indicate that the product is a skin, respiratory and severe eye irritant. Acute dermal irritation has been reported in human studies. Animal ingestion and inhalation studies have given rise to the consistent observation of cancers (of the brain and spinal cord, ear canal, gastrointestinal tract and mammary glands), including upon the administration of non-toxic doses. Increases in cancer incidence have not been confirmed in epidemiological studies involving exposed workers, in part due to the limited number of published studies.
Descriptors (primary) IPCS; toxicology; acrylonitrile
Descriptors (secondary) toxic effects; literature survey; irritants; epidemiological aspects; ILO; criteria document; WHO; cancer; ecotoxicology; animal experiments; UNEP
Document type B - Chemical safety information sheets
Country / State or ProvinceWHO
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Cyano compounds