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Document ID (ISN)78597
CIS number 02-660
ISSN - Serial title 1219-1221 - Central European Journal of Occupational and Environmental Medicine
Year 2001
Convention or series no.
Author(s) Saad A., Besher S., Ammar N., Emam H.
Title Therapeutic effects of Nigella sativa on occupational contact dermatitis
Bibliographic information 2001, Vol.7, No.1, p.26-38. Illus. 42 ref.
Abstract Nigella seeds have known anti-allergic effects in traditional medicine. The therapeutic effects of Nigella sativa powdered in the form of capsules, lipoidal matter extract and the aqueous alcoholic extract of nigella seeds in the form of two ointments were studied in 50 male volunteers aged between 25 and 55 years suffering from chronic occupational contact dermatitis. Blood picture, IgE and natural killer (NK) cells were recorded before and after two weeks of therapy. Treatment with lipoidal extract ointment, alcoholic extract ointment and powdered seed capsules led to complete recovery of the eczematous lesions in 89%, 46%, and 63%, respectively. Clinical improvement by these three treatments was statistically significant, while placebos achieved no significant improvement. NK cell fraction was significantly augmented in treated groups. No harmful effects on the liver and the kidney functions were found.
Descriptors (primary) medicinal plants; eczema; skin allergies
Descriptors (secondary) immunoglobulins; comparative study; medical treatment
Document type D - Periodical articles
Country / State or ProvinceEgypt
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Allergies
Skin diseases