|Document ID (ISN)||78505|
|ISSN - Serial title
||0355-3140 - Scandinavian Journal of Work, Environment and Health
|Convention or series no.
||Kristensen P., Andersen A., Irgens L.M.
||Hormone-dependent cancer and adverse reproductive outcomes in farmers' families - Effects of climatic conditions favoring fungal growth in grain
||Aug. 2000, Vol.26, No.4, p.331-337. 24 ref.
||The impact of grain farming and climate on late-term abortion among female farmers, male genital birth defects among their sons, and hormone-dependent cancer among male and female farmers and their adult children was investigated. 246,043 male and female farmers born between 1925 and 1971 and 264,262 of their offspring were identified from the Norwegian national registers. Categories of high exposure were associated with adverse reproductive outcomes and cancer among female farmers, the strongest occurring for late-term abortion (Odds Ratio (OR) 2.6). Exposure associations for ovarian and breast cancer, and male genital defects, were more moderate. Endometrial cancer was associated with grain farming (OR 2.0). Exposure associations for cancer were strongest for pre-menopausal, parous women. The results are consistent with hormonal effects of inhaled mycotoxins during pregnancy.
||cereal farming; antifertility effects; cancer; hormones; mycotoxins
||climate; ovarian cancer; Norway; children; diseases of genital organs; carcinogenic effects; uterine cancer; breast cancer; cohort study; short-term exposure; expectant mothers; abortion
||D - Periodical articles
|Country / State or Province||Norway|
||Agriculture, fishing, animal husbandry
|Broad subject area(s)
||Industries and occupations
||Antifertility and prenatal effects
Genetic factors in reaction to exposures