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CISDOC database
Document ID (ISN) | 78421 |
CIS number |
02-543 |
Year |
1997 |
Convention or series no. |
Fiche toxicologique No.46
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Title |
Tolylene diisocyanate |
Original title |
Diisocyanate de toluylène [in French] |
Bibliographic information |
Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, CD-ROM CD 613, May 2000. Rev.ed. 4p. Illus. 24 ref. |
Abstract |
Chemical safety information sheet. Update of data sheet already summarized in CIS 87-440. Tolylene diisocyanate (TDI) is usually a mixture of 80% tolylene 2,4-diisocyanate and 20% tolylene 2,6-diisocyanate. Acute toxicity: splashes may cause severe skin and eye lesions; irritation of ocular, respiratory tract and digestive mucous membranes; bronchial irritation (cough, asthmatic dyspnoea); neurological signs; delayed pulmonary oedema. Chronic toxicity: contact dermatitis; allergic asthma; respiratory disorders; delayed pulmonary oedema; bronchopneumonia; restrictive ventilatory impairment; sensitization. Exposure limits: France: TWA = 0.08mg/m3 (0.010ppm); ceiling value (5min) = 0.16mg/m3 (0.020ppm); USA (ACGIH, 1996): TWA for tolylene 2,4-diisocyanate = 0.005ppm. EEC number and mandatory labelling codes: No.615-006-00-4; T, R23, R36/37/38, R42, S23, S26, S28, S38, S45, 209-544-4, 202-039-0. The complete datasheet collection on CD-ROM has been analysed under CIS 01-201. |
Descriptors (primary) |
threshold limit values; 2,4-tolylene diisocyanate; 2,6-tolylene diisocyanate; France |
Descriptors (secondary) |
dangerous substances; pulmonary oedema; sensitization dermatitis; fire hazards; toxicology; restrictive ventilatory impairment; allergic asthma; bronchopneumonia; labelling; limitation of exposure; waste disposal; chemical burns; first aid; personal protective equipment; spills; delayed effects; health hazards; legislation; sampling and analysis; data sheet; irritants |
Document type |
B - Chemical safety information sheets |
Country / State or Province | France |
Subject(s) |
Toxic and dangerous substances
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Broad subject area(s) |
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Browse category(ies) |
Occupational exposure limits Isocyanates Cyano compounds
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