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Document ID (ISN)78421
CIS number 02-543
Year 1997
Convention or series no. Fiche toxicologique No.46
Title Tolylene diisocyanate
Original title Diisocyanate de toluylène [in French]
Bibliographic information Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, CD-ROM CD 613, May 2000. Rev.ed. 4p. Illus. 24 ref.
Abstract Chemical safety information sheet. Update of data sheet already summarized in CIS 87-440. Tolylene diisocyanate (TDI) is usually a mixture of 80% tolylene 2,4-diisocyanate and 20% tolylene 2,6-diisocyanate. Acute toxicity: splashes may cause severe skin and eye lesions; irritation of ocular, respiratory tract and digestive mucous membranes; bronchial irritation (cough, asthmatic dyspnoea); neurological signs; delayed pulmonary oedema. Chronic toxicity: contact dermatitis; allergic asthma; respiratory disorders; delayed pulmonary oedema; bronchopneumonia; restrictive ventilatory impairment; sensitization. Exposure limits: France: TWA = 0.08mg/m3 (0.010ppm); ceiling value (5min) = 0.16mg/m3 (0.020ppm); USA (ACGIH, 1996): TWA for tolylene 2,4-diisocyanate = 0.005ppm. EEC number and mandatory labelling codes: No.615-006-00-4; T, R23, R36/37/38, R42, S23, S26, S28, S38, S45, 209-544-4, 202-039-0. The complete datasheet collection on CD-ROM has been analysed under CIS 01-201.
Descriptors (primary) threshold limit values; 2,4-tolylene diisocyanate; 2,6-tolylene diisocyanate; France
Descriptors (secondary) dangerous substances; pulmonary oedema; sensitization dermatitis; fire hazards; toxicology; restrictive ventilatory impairment; allergic asthma; bronchopneumonia; labelling; limitation of exposure; waste disposal; chemical burns; first aid; personal protective equipment; spills; delayed effects; health hazards; legislation; sampling and analysis; data sheet; irritants
Document type B - Chemical safety information sheets
Country / State or ProvinceFrance
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Occupational exposure limits
Cyano compounds