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Document ID (ISN)78390
CIS number 02-733
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2002
Convention or series no.
Author(s) Wouters I.M., Hilhorst S.K.M., Kleppe P., Doekes G., Douwes J., Peretz C., Heederik D.
Title Upper airway inflammation and respiratory symptoms in domestic waste collectors
Bibliographic information Feb. 2002, Vol.59, No.2, p.106-112. Illus. 38 ref.
Abstract In a cross sectional study among 47 waste collectors and 15 controls, questionnaire data on respiratory symptoms were collected. Nasal lavage (NAL) was performed before and after a work shift at the beginning and at the end of the working week. In NAL fluid, cells were counted and differentiated and concentrations of interleukin 6 and 8 (IL6, IL8), tumour necrosis factor-α (TNFα), and IL1β were measured. In collectors, inhalable dust samples were collected in which bacterial endotoxin and mould β(1⇒3)-glucan were assessed. Waste collectors show signs of increased upper airway inflammation and respiratory symptoms compared with controls. Geometric mean exposure concentrations were 0.58mg/m3 for dust, 39EU/m3 for endotoxin, and 1.3µg/m3 for β(1⇒3)-glucan. At the end of the week collectors had higher concentrations of total cells and IL8 in NAL before and after a shift than controls. However, concentrations of IL6, TNFα, and IL1β were not associated with symptoms or exposure.
Descriptors (primary) upper respiratory diseases; garbage collectors; risk factors; biological hazards
Descriptors (secondary) interleukins; bacterial toxins; occupation disease relation; symptoms; determination in biological matter; questionnaire survey; case-control study; cross-sectional study; air sampling; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceIsrael; Netherlands
Subject(s) Commerce, services, offices
Broad subject area(s) Industries and occupations
Browse category(ies) Biological hazards
Diseases of the respiratory system (except for pneumoconiosis & similar)