|Document ID (ISN)||78390|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Wouters I.M., Hilhorst S.K.M., Kleppe P., Doekes G., Douwes J., Peretz C., Heederik D.
||Upper airway inflammation and respiratory symptoms in domestic waste collectors
||Feb. 2002, Vol.59, No.2, p.106-112. Illus. 38 ref.
||In a cross sectional study among 47 waste collectors and 15 controls, questionnaire data on respiratory symptoms were collected. Nasal lavage (NAL) was performed before and after a work shift at the beginning and at the end of the working week. In NAL fluid, cells were counted and differentiated and concentrations of interleukin 6 and 8 (IL6, IL8), tumour necrosis factor-α (TNFα), and IL1β were measured. In collectors, inhalable dust samples were collected in which bacterial endotoxin and mould β(1⇒3)-glucan were assessed. Waste collectors show signs of increased upper airway inflammation and respiratory symptoms compared with controls. Geometric mean exposure concentrations were 0.58mg/m3 for dust, 39EU/m3 for endotoxin, and 1.3µg/m3 for β(1⇒3)-glucan. At the end of the week collectors had higher concentrations of total cells and IL8 in NAL before and after a shift than controls. However, concentrations of IL6, TNFα, and IL1β were not associated with symptoms or exposure.
||upper respiratory diseases; garbage collectors; risk factors; biological hazards
||interleukins; bacterial toxins; occupation disease relation; symptoms; determination in biological matter; questionnaire survey; case-control study; cross-sectional study; air sampling; exposure evaluation
||D - Periodical articles
|Country / State or Province||Israel; Netherlands|
||Commerce, services, offices
|Broad subject area(s)
||Industries and occupations
Diseases of the respiratory system (except for pneumoconiosis & similar)