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Document ID (ISN)78382
CIS number 02-706
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 2000
Convention or series no.
Author(s) Engel L.S., O'Meara E.S., Schwartz S.M.
Title Maternal occupation in agriculture and risk of limb defects in Washington State, 1980-1993
Bibliographic information June 2000, Vol.26, No.3, p.193-198. 10 ref.
Abstract A retrospective cohort study was conducted using birth records from the state of Washington (USA) for the years 1980 through 1993. The exposed group, consisting of 4466 births to mothers employed in agriculture, was compared with 2 reference groups. The outcome of interest was limb defects (syndactyly, polydactyly, adactyly, and "other limb reductions" as listed in the birth record). An elevated risk of limb defects was observed for the exposed group in comparison with the reference groups. These results support the hypothesis that maternal occupational exposure to agricultural chemicals may increase the risk of giving birth to a child with limb defects.
Descriptors (primary) agricultural chemicals; parental exposure; agriculture; expectant mothers; teratogenic effects
Descriptors (secondary) USA; case-control study; Washington; lower extremities; cohort study
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Industries and occupations
Browse category(ies) Agricultural chemicals
Genetic factors in reaction to exposures
Antifertility and prenatal effects