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Document ID (ISN)78367
CIS number 02-836
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2001
Convention or series no.
Author(s) Chen W., Zhuang Z., Attfield M.D., Chen B.T., Gao P., Harrison J.C., Fu C., Chen J.Q., Wallace W.E.
Title Exposure to silica and silicosis among tin miners in China: Exposure-response analyses and risk assessment
Bibliographic information Jan. 2001, Vol.58, No.1, p.31-37. Illus. 21 ref.
Abstract A cohort study of 3010 miners exposed to silica dust and employed for at least 1 year during 1960-5 in one of four Chinese tin mines was conducted. There were 1015 miners identified with silicosis. Among these, 684 developed silicosis after exposure ended (a mean of 3.7 years after). The risk of silicosis was strongly related to cumulative exposure to silica dust, with the risk of silicosis less than 0.1% when the Chinese measure of cumulative exposure to total dust (CTD) was under 10mg/m3-years (or 0.36mg/m3-years of respirable crystalline silica), increasing to 68.7% when CTD exposure was 150mg/m3-years (or 5.4mg/m3-years of respirable crystalline silica). Latency period was not correlated to the risk of silicosis or cumulative dose of exposure. This study predicts an approximate cumulative risk of silicosis of 36% for a 45 year lifetime exposure to these tin mine dusts at the CTD exposure standard of 2mg/m3, and a 55% risk at 45 years exposure to the current United States standards of 0.1mg/m3 100% respirable crystalline silica dust.
Descriptors (primary) China; silica; hazard evaluation; silicosis; underground mining
Descriptors (secondary) threshold limit values; respirable dust; dose-response relationship; cohort study; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceChina; USA
Subject(s) Mines and quarries
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation
Pneumoconioses