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Document ID (ISN)78121
CIS number 02-432
ISSN - Serial title 0022-1899 - Journal of Infectious Diseases
Year 2000
Convention or series no.
Author(s) Chew M.H.L., Arguin P.M., Shay D.K., Rollin P.E., Shieh.W.J., Zaki S.R., Rota P.A., Ling A.E., Ksiazek T.G., Chew S.K., Anderson L.J.
Title Risk factors for Nipah virus infection among abattoir workers in Singapore
Bibliographic information 2000, No.181, p.1760-1763. 14 ref.
Abstract During 10-19 March 1999, 11 workers in one of two Singapore abattoirs developed Nipah-virus-associated encephalitis or pneumonia, resulting in one death. A case-control study was conducted to determine occupational risk factors for infection. Case patients were workers from the affected abattoir who had anti-Nipah IgM antibodies; control subjects were randomly selected workers from the same abattoir who tested negative for anti-Nipah IgM. All 13 case patients versus 26 (63%) of 41 control subjects reported contact with live pigs. No unusual illnesses among pigs processed during February-March were reported. Contact with live pigs appeared to be the most important risk factor for human Nipah virus infection. In the other abattoir where no case was reported, the use of face shields increased among eviscerators 3-4 months before the outbreak. Direct contact with live, potentially infected pigs should be minimized to prevent transmission of this potentially fatal zoonosis to humans.
Descriptors (primary) viruses; zoonoses; risk factors; slaughtering; contagion
Descriptors (secondary) Singapore; virus diseases; fatalities; case-control study; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceSingapore; USA
Subject(s) Food, beverage and tobacco industries
Broad subject area(s) Biological hazards
Browse category(ies) Zoonoses
Bacterial and parasitic diseases
Viral diseases (other than aids)