| Document ID (ISN) | 78078 |
| CIS number |
02-323 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
2000 |
| Convention or series no. |
|
| Author(s) |
Tulinska J., Dusinska M., Jahnova E., Liskova A., Kuricova M., Vodicka P., Vodickova L., Sulcova M., Fuortes L. |
| Title |
Changes in cellular immunity among workers occupationally exposed to styrene in a plastics lamination plant |
| Bibliographic information |
Nov. 2000, Vol.38, No.5, p.576-583. 20 ref. |
| Abstract |
Immune and haematological parameters were examined in 29 hand laminators and sprayers exposed to styrene for an average of 14 years and in 19 unexposed controls. The workers were located in a production area with an average area airborne styrene level of 139.5mg/m3. Mean concentration of styrene in the blood of exposed workers was 945.7µg/L and the mean styrene in exhaled air was 38.8µg/L. Parameters of internal and external exposure, immune function assays, immunoglobulins and haematology were evaluated in exposed and non-exposed populations. Styrene concentrations in both blood and exhaled air were associated with decreased percentage of large granular lymphocytes. These results suggest immune alterations of cell-mediated immune response of T-lymphocytes and imbalance in leucocyte subsets in peripheral blood of workers exposed to styrene. |
| Descriptors (primary) |
styrene; plastics converting industry; immunology; haematological changes |
| Descriptors (secondary) |
lymphocytes; immunoglobulins; exposure evaluation; determination in exhaled air; determination in air; determination in blood; exposure tests; long-term exposure |
| Document type |
D - Periodical articles |
| Country / State or Province | Czech Republic; Slovak Republic; USA |
| Subject(s) |
Chemicals, plastics and rubber
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Blood diseases
Aromatic hydrocarbons
|
