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Document ID (ISN)78051
CIS number 02-171
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2001
Convention or series no.
Author(s) Goldberg M.S., Parent M.E., Siemiatycki J., DÚsy M., Nadon L., Richardson L., Lakhani R., Latreille B, Valois M.F.
Title A case-control study of the relationship between the risk of colon cancer in men and exposures to occupational agents
Bibliographic information June 2001, Vol.39, No.6, p.531-546. 99 ref.
Abstract A population-based case-control study was conducted to explore associations between occupational circumstances and several cancer sites, including the colon. 497 male patients with a confirmed diagnosis of colon cancer, 1514 controls with cancers at other sites, and 533 population-based controls were interviewed. Detailed job histories and relevant potential confounding variables were obtained, and the job histories were translated by a team of chemists and industrial hygienists into a history of occupational exposures. There was reasonable evidence of an association between colon cancer and occupation for men employed in nine industry groups (adjusted odds ranging from 1.1 to 1.6 per 10-year increase in duration of employment), and in 12 job groups (OR varying from 1.1 to 1.7). In addition, evidence of increased risks by increasing level of exposures to 21 occupational agents was found, the most significant being polystyrene, polyurethanes, coke dust, mineral oils and polyacrylates.
Descriptors (primary) occupation disease relation; exposure; gastrointestinal cancer
Descriptors (secondary) epidemiology; chemical products; white-collar workers; case-control study; hazard evaluation
Document type D - Periodical articles
Country / State or ProvinceCanada
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Gastrointestinal diseases