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Document ID (ISN)77978
CIS number 02-278
ISSN - Serial title 1877-7856 - Encyclopédie médico-chirurgicale
Year 2000
Convention or series no. Fascicule 16-059-D-30, 2-2000
Author(s) Pontal P.G.
Title Herbicides
Original title Herbicides [in French]
Bibliographic information Toxicologie-Pathologie professionnelle, 2nd Quarter 2000, No.127, 10p. 57 ref.
Abstract Herbicides represent roughly 50% of the pesticides used in agriculture. The effect most frequently observed in animal studies is hepatic enzyme induction, possibly associated with hepatoxicity at high doses. Apart from accidental poisoning or suicides, the most common findings in human studies are allergic or irritant skin effects. Despite numerous epidemiological studies attempting to establish a link between exposure to pesticides and cancers or reproductive disorders, there were no conclusive findings. Herbicide contamination can occur during their manufacture, in agricultural operations or at the consumer level, due to the possible existence of residues or metabolites in treated plants. For each contamination path and for each product or formulation, specific rules indicate the acceptable exposure limits, conditions of use and labelling requirements.
Descriptors (primary) toxic effects; herbicides; toxic substances; toxicology; France
Descriptors (secondary) literature survey; pesticide poisoning; threshold limit values; irritants; skin allergies; dermatitis; encyclopaedia; hepatic diseases; labelling; limitation of exposure; epidemiologic study; animal experiments; toxic metabolites
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals