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Document ID (ISN)77942
CIS number 02-216
ISSN - Serial title 1877-7856 - Encyclopédie médico-chirurgicale
Year 2001
Convention or series no. Fascicule 16-535-G-20
Author(s) Malo J.L., Gautrin D., Lemière C., Cartier A.
Title Occupational asthma with and without latency
Original title Asthme professionnel avec et sans période de latence [in French]
Bibliographic information Toxicologie-Pathologie professionnelle, 1st Quarter 2001, No.130, 7p. Illus. 78 ref.
Abstract There are two types of occupational asthma (OA): OA with latency necessary for sensitization, the most commonly encountered form, and OA without latency, also called the bronchial irritation syndrome (BIS), which occurs following single or multiple inhalation accidents where the worker develops asthmatic symptoms with persistent bronchial hyperactivity. Clinical investigation of OA with latency follows a series of tests based on decision charts. Among the various predisposition factors, atopy alone favours the emergence of OA to high molecular-weight substances (proteins), even after an end to the exposure, particularly if the exposure occurred over long periods and workers were not removed soon enough from the source of exposure upon the appearance of symptoms. The use of anti-inflammatory agents improves the outcome. BIS is caused by inhalation of irritant substances at high levels of concentration. This type of exposure gives rise to asthmatic symptoms and persistent bronchial hyperactivity.
Descriptors (primary) occupational diseases; France; sensitization; asthma; latency
Descriptors (secondary) allergens; irritants; allergies; limitation of exposure; short-term exposure; allergic reactivity; transfer to other work; individual susceptibility; encyclopaedia; data sheet; allergic respiratory disorders; long-term exposure
Document type F - Information notes, codes of practice, standards
Country / State or ProvinceCanada
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)