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Document ID (ISN)77938
CIS number 02-276
ISSN - Serial title 1120-2971 - Prevenzione oggi
Year 2000
Convention or series no.
Author(s) Leoni V., Petyx M., Rossini A., Urso M., Materazzo F., Ensabella F., Vitali M., Fabiani L., Giuliani A.R., Testa A., Ranaldi R., De Marco A., Owczarek M., De Simone L., Guidotti M., Serva M.
Title Occupational and environmental risks related to activities of diagnostic laboratories and their prevention. Cytogenetic and environmental mutagenicity tests
Original title Rischio e prevenzione occupazionale e ambientale correlato [sic] alle attivitÓ dei laboratori diagnostici. Test citogenetici e di mutagenesi ambientale [in Italian]
Bibliographic information 2000, Vol.12, No.4, p.35-112. Illus. Bibl. ref.
Abstract A report on a survey to gather information on types, numbers and techniques of diagnostic analysis and on the collection of waste products in two Italian hospitals. Cytogenetic tests were carried out on 50 exposed workers in the laboratories of these hospitals and on 50 controls. Altogether approximately 150 diagnostic techniques were recorded, together with about 300 reagents used in these procedures and classified according their toxicity and risk potential. Mutagenicity and cytogenicity tests were also carried out for the same substances. Of the reagents recorded, 40% can produce burns, 28% are toxic by inhalation or ingestion, 12% are flammable and 4% are carcinogenic. Among the waste products, the most harmful were those coming from microbiological and enzyme tests. Cytogenetic tests proved their usefulness as aspecific indicators of increased risk of harmful exposures. As useful outcomes of the study, the preparation of two questionnaires should also be noted: one on the analytical methods and substances used and the wastes produced by laboratories, the other on the identification of exposed and non-exposed subjects for epidemiological surveys.
Descriptors (primary) disposal of harmful waste; laboratory work; reagents; test laboratories; cytogenetic studies; mutagenicity tests; hospitals; health care personnel; risk factors; disposal of radioactive waste
Descriptors (secondary) Italy; toxicity evaluation; list of chemical substances; epidemiology
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Waste collection and disposal
Health care services