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Document ID (ISN)77538
CIS number 01-1492
ISBN(s) 92-832-1273-8
Year 1999
Convention or series no. IARC Monographs 73
Author(s)
World Health Organization (WHO)
Title IARC monographs on the evaluation of carcinogenic risks to humans - Some chemicals that cause tumours of the kidney or urinary bladder in rodents and some other substances
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, International Agency for Research on Cancer (IARC), 150 cours Albert Thomas, 69372 Lyon Cedex 08, France, 1999. iv, 674p. Illus. Bibl.ref. Index.
Abstract This monograph presents the views and expert opinions of an IARC working group which met in Lyon, France, 13-20 October 1998. 21 chemicals or classes of chemicals were reviewed: eight were rated 2B (possibly carcinogenic to humans) and 13 were classified 3 (not classifiable as to its carcinogenicity to humans). For each chemical, the following aspects are covered: exposure data; studies of cancer in humans; studies of cancer in experimental animals; other data relevant to an evaluation of carcinogenicity and its mechanisms; summary of reported data and evaluation. The chemicals are: allyl isothiocyanate; ortho-anisidine; atrazine; butyl benzyl phthalate; chloroform; chlorothalonil (= 2,4,5,6-tetrachloroisophthalonitrile); cyclamates; dichlorobenzenes; hexachlorobutadiene; hexachloroethane; d-limonene; melamine; methyl tert-butyl ether; nitrilotriacetic acid and its salts; paracetamol (= acetaminophen); ortho-phenylphenol and its sodium salt; potassium bromate; quercetin; saccharin and its salts; simazine.
Descriptors (primary) WHO; IARC; carcinogenic effects; hazard evaluation; chemical products
Descriptors (secondary) mutagenic effects; benzyl butyl phthalate; acetaminophen; chloroform; hexachloroethane; m-dichlorobenzene; o-dichlorobenzene; p-dichlorobenzene; methyl t-butyl ether; d-limonene; potassium bromate; melamine; atrazine; simazine; saccharin; calcium saccharin; sodium saccharin; 2,4,5,6-tetrachloroisophthalonitrile; cyclamates; quercetin; nitrilotriacetic acid; o-anisidine; 2-phenylphenol; sodium 2-biphenylolate; animal experiments; human experiments; hexachlorobutadiene; allyl isothiocyanate; criteria document; chlorobenzenes
Document type E - Books, reports, proceedings
Country / State or ProvinceFrance
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation
IARC Monographs
Genetic factors in reaction to exposures