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Document ID (ISN)77500
CIS number 01-1433
ISSN - Serial title 0949-8036 - Gefahrstoffe Reinhaltung der Luft
Year 1998
Convention or series no.
Author(s) Wolf J., Fengel D., Klein R.G., Scheithauer M., Schmezer P., Schroeder H.G., Woeste W.
Title Aetiology of nasal cancer in the woodworking industry
Original title Zur Frage der ─tiologie von Nasentumoren in der Holzwirtschaft [in German]
Bibliographic information Nov.-Dec. 1998, Vol.58, No.11-12, p.455-461. Illus. 17 ref.
Abstract In order to be able to differentiate between the effects on nasal tissue of oak- and beechwood dust from those of lacquers, solvents, wood preservatives and glues used in the woodworking industry, the following studies were conducted: the changes of the nasal tissue of workers exposed to oak- and beechwood dust with and without additional exposure to other substances were determined and compared with those in an unexposed control group. Hyperplasias of the cylindrical cells were significantly more frequent in woodworkers than in the non-exposed group. Of the 144 woodworkers examined, 105 were found to be also exposed to wood preservatives. The latency period for the development of adenocarcinoma of the nose was found to be 40-44 years. In animal testing, malignant tumours were observed only in animals exposed to solvents-containing wood preservatives in addition to oakwood dust.
Descriptors (primary) hardwoods; woodworking industry; nasal cancer; aetiology
Descriptors (secondary) wood preservatives; wood dust; genetic effects; epidemiologic study; animal experiments; multifactor aetiology
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Woodworking industry
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Woodworking industry
Lumber and the woodworking industry
Genetic factors in reaction to exposures