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Document ID (ISN)76781
CIS number 01-666
ISSN - Serial title 1877-7856 - Encyclopédie médico-chirurgicale
Year 1994
Convention or series no. Fascicule 16-002-A-30
Author(s) Javelaud B.
Title Arsenic and its compounds
Original title Arsenic et dérivés [in French]
Bibliographic information Toxicologie-Pathologie professionnelle, 4th Quarter 1994, No.105, 7p. 82 ref.
Abstract Toxicological data sheet on arsenic (As) and its compounds. Metallic arsenic is non-toxic and does not oxidize. The main toxic compounds of As are trivalent, including arsenic trioxide, sodium arsenite and potassium arsenite. The toxicity of pentavelent compounds is less than that of trivalent compounds. Main exposure routes: inhalation, ingestion. Acute toxicity: vomiting, abdominal pain and diarrhoea, followed by cardiovascular symptoms; death from ventricular fibrillation occurs within 10 hours following ingestion; lethal dose is estimated at 1-2mg/kg. Chronic toxicity: effects on the skin; neurotoxic effects; inhalation of arsenical dusts or vapours can give rise to bronchial cancer; liver cancer; cardiovascular effects; haematological effects; effects on the reproductive system. The toxicology of arsine is covered in a specific section. Tables concerning the compensation of occupational diseases caused by arsenic are included.
Descriptors (primary) occupational diseases; toxicology; arsenic and compounds; France
Descriptors (secondary) neurotoxic effects; arsenic trioxide; arsenic; sodium arsenite; arsine; ingestion; inhalation; bronchial cancer; liver cancer; lethal dose 50; chromosome changes; haematological effects; chronic toxicity; workmen's compensation; cardiotoxic effects; potassium arsenite; encyclopaedia; data sheet; acute toxicity
Document type B - Chemical safety information sheets
Country / State or ProvinceFrance
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Genetic factors in reaction to exposures
Arsenic and compounds
Inorganic substances