|Document ID (ISN)||76628|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Relation between exposure to asbestos and smoking jointly and the risk of lung cancer
||Mar. 2001, Vol.58, No.3, p.145-153. 37 ref.
||To review evidence of the relationship between the combined effect of exposure to asbestos and smoking on the risk of lung cancer, 23 studies epidemiological studies were analysed, comparing the risk of lung cancer in subjects unexposed to asbestos or smoking, exposed to asbestos only, to smoking only, or to both. Eight studies provided insufficient data. Asbestos exposure was associated with a significantly increased risk in non-smokers in six of the remaining studies and with a moderate increase in a further six. In two of the three studies that found no increase, asbestos exposure was insufficient to increase risks in smokers. In 30 of 31 data sets analysed, risk in the combined exposure group was greater than predicted by the additive model. Asbestos exposure multiplies risk of lung cancer by a similar factor in non-smokers and smokers.
||asbestos; hazard evaluation; lung cancer; smoking
||D - Periodical articles
|Country / State or Province||United Kingdom|
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)