|Document ID (ISN)||76524|
|ISSN - Serial title
||1575-1392 - Prevenciˇn, trabajo y salud
|Convention or series no.
||de la Iglesia Huerta A., Delgado Cobos P.
||Pesticides: Neurotoxicity and heath surveillance
||Plaguicidas: Neurotoxicidad y vigilancia de la salud [in Spanish]|
||2000, No.8, p.4-14. Illus. 50 ref.
||Spain is the fifth largest consumer of crop protection products in Europe, of which 80% are organophosphorus compounds. The aetiology and pathogenesis of this class of compounds is described. The most important mode of poisoning is through skin absorption, while ingestion is mainly by accident or a result of poor hygiene, and inhalation risk is a function of the products' volatility. The immediate effects of poisoning are muscarinic and nicotinic effects, as well as neurological effects. Neurotoxic effects may be delayed, and can appear several days or weeks after the poisoning. For this reason, regular medical checks and biological monitoring are necessary, in particular the determination of plasmatic acetylcholinesterase and cholinesterase, and the detection of possible urinary metabolites, in order to evaluate exposure. Use of the Peradeniya scale, which assigns ratings to five organophosphorus poisoning symptoms, enables the determination of the severity of the poisoning.
||neurotoxic effects; medical supervision; pesticides; pesticide poisoning
||cholinesterase monitoring; Spain; organophosphorus compounds; exposure evaluation; skin absorption; diagnosis; cholinesterase
||D - Periodical articles
|Country / State or Province||Spain|
||Toxic and dangerous substances
|Broad subject area(s)
||Diseases of the nervous system