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Document ID (ISN)76342
CIS number 01-420
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1996
Convention or series no.
Author(s) Blatter B.M., Roeleveld N., Zielhuis G.A., GabreŰls F.J.M., Verbeek A.L.M.
Title Maternal occupational exposure during pregnancy and the risk of spina bifida
Bibliographic information Feb. 1996, Vol.53, No.2, p.80-86. 23 ref.
Abstract A case-control study was carried out to explore associations between spina bifida and occupational exposure of the mother. Cases were 470 children with spina bifida aperta born between 1980 and 1992 from nine hospitals in the Netherlands. The controls were 2350 children born healthy in the same period as the cases. Analyses of occupation showed an increased risk for women working in agricultural occupations (OR = 3.4) and, although less distinct, for cleaning women (OR = 1.7). Only a few mothers of cases seemed to be occupationally exposed to chemical or physical agents. No differences in occurrence of specific exposures could be detected between cases and controls. Besides, no differences were seen in pesticide or disinfectant exposure among case and control mothers in agricultural occupations.
Descriptors (primary) parental exposure; occupation disease relation; expectant mothers; teratogenic effects; genetic effects
Descriptors (secondary) Netherlands; children; domestic and related helpers, cleaners; case-control study; agriculture; pesticides
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Antifertility and prenatal effects
Domestic workers
Genetic factors in reaction to exposures