|Document ID (ISN)||76342|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Blatter B.M., Roeleveld N., Zielhuis G.A., GabreŰls F.J.M., Verbeek A.L.M.
||Maternal occupational exposure during pregnancy and the risk of spina bifida
||Feb. 1996, Vol.53, No.2, p.80-86. 23 ref.
||A case-control study was carried out to explore associations between spina bifida and occupational exposure of the mother. Cases were 470 children with spina bifida aperta born between 1980 and 1992 from nine hospitals in the Netherlands. The controls were 2350 children born healthy in the same period as the cases. Analyses of occupation showed an increased risk for women working in agricultural occupations (OR = 3.4) and, although less distinct, for cleaning women (OR = 1.7). Only a few mothers of cases seemed to be occupationally exposed to chemical or physical agents. No differences in occurrence of specific exposures could be detected between cases and controls. Besides, no differences were seen in pesticide or disinfectant exposure among case and control mothers in agricultural occupations.
||parental exposure; occupation disease relation; expectant mothers; teratogenic effects; genetic effects
||Netherlands; children; domestic and related helpers, cleaners; case-control study; agriculture; pesticides
||D - Periodical articles
|Country / State or Province||Netherlands|
|Broad subject area(s)
||Occupational medicine, epidemiology
||Antifertility and prenatal effects
Genetic factors in reaction to exposures