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CISDOC database

Document ID (ISN)76324
CIS number 01-503
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2000
Convention or series no.
Author(s) Kamel F., Boyes W.K., Gladen B.C., Rowland A.S., Alavanja M.C.R., Blair A., Sandler D.P.
Title Retinal degeneration in licensed pesticide applicators
Bibliographic information June 2000, Vol.37, No.6, p.618-628. 20 ref.
Abstract Retinal degeneration is the leading cause of visual impairment in older adults. In a cohort of licensed pesticide applicators in the US, cross-sectional data from self administered questionnaires given at enrollment in 1994-1996 were used to compare pesticide use in 154 applicators who reported retinal degeneration and 17,804 controls. Retinal degeneration was associated with fungicide use (odds ratio = 1.8). This relationship was seen in subgroups defined by state of residence, demographic characteristics and medical history, as well as in the entire group. Risk increased with cumulative days of fungicide use and was greater when application methods involving greater personal exposure were used. Less significant retinal degeneration was also related to use of organochlorine or carbamate insecticides. These results suggest that exposure to some fungicides and insecticides may increase the risk of retinal degeneration.
Descriptors (primary) retinal damage; pesticide spraying; hazard evaluation; amblyopia
Descriptors (secondary) USA; chlorinated organic compounds; carbamates; cohort study; fungicides; questionnaire survey; insecticides
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation
Diseases of the eye and vision damage