ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)76316
CIS number 01-418
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Ojajńrvi I.A., Partanen T.J., Kauppinen T.P., Ahlbom A., Wesseling C.H., Weiderpass E., Boffetta P., Vainio H.U., Hakulinen T., Jourenkova N., Kogevinas M., Porta M.
Title Occupational exposures and pancreatic cancer: A meta-analysis
Bibliographic information May 2000, Vol.57, No.5, p.316-324. Illus. 102 ref.
Abstract Epidemiological studies on pancreatic cancer and worksite exposures during 1969-98 were surveyed. Exposure to chlorinated hydrocarbon (CHC) solvents and related compounds was associated with a risk ratio of 1.4, and nickel and nickel compounds with a risk ratio of 1.9. Excesses were also found for chromium and chromium compounds (1.4), polycyclic aromatic hydrocarbons (PAHs) (1.5), organochlorine insecticides (1.5), silica dust (1.4), and aliphatic and alicyclic hydrocarbon solvents (1.3). The occupational aetiological fraction of pancreatic cancer was estimated at 12%. In a subpopulation exposed to CHC solvents and related compounds, it was 29%; to chromium and chromium compounds, 23%; to nickel and nickel compounds, 47%; to insecticides, 33%; and to PAHs, 33%. Further studies are warranted on the interactions between occupational, environmental and lifestyle factors as well as interactions between genes and the environment.
Descriptors (primary) harmful substances; exposure; tumour of the pancreas
Descriptors (secondary) literature survey; nickel and compounds; chromium and compounds; silica; chlorinated hydrocarbons; aromatic hydrocarbons
Document type D - Periodical articles
Country / State or ProvinceCosta Rica; Spain; Finland; France; Sweden
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Endocrine diseases