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CISDOC database

Document ID (ISN)76310
CIS number 01-417
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Freedman D.M., Dosemeci M., Alavanja M.C.R.
Title Mortality from multiple sclerosis and exposure to residential and occupational solar radiation: A case-control study based on death certificates
Bibliographic information June 2000, Vol.56, No.6, p.418-421. 27 ref.
Abstract To explore whether mortality from multiple sclerosis is negatively associated with exposure to sunlight, two case-control studies based on death certificates were conducted for mortality from multiple sclerosis and non-melanoma skin cancer (as a positive control). Cases were all deaths from multiple sclerosis between 1984 and 1995 in 24 states of the United States. Controls excluded cancer and certain neurological deaths. Results were adjusted for age, sex, race and socio-economic status. Unlike mortality from skin cancer, mortality from multiple sclerosis was negatively associated with residential exposure to sunlight (odds ratio 0.53 (multiple sclerosis) and 1.24 (skin cancer)). Odds ratios for the highest occupational exposure to sunlight were 0.74 for mortality from multiple sclerosis, compared with 1.21 for mortality from non-melanoma skin cancer. The OR was 0.24 for the combined effect of the highest levels of residential, and occupational exposure to sunlight on multiple sclerosis, compared with an OR of 1.38 for skin cancer.
Descriptors (primary) solar radiation; hazard evaluation; multiple sclerosis; mortality
Descriptors (secondary) aetiology; case-control study; outdoor work
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Radiation
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the nervous system
Non-ionizing radiation
Risk evaluation