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CISDOC database

Document ID (ISN)76302
CIS number 01-486
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2000
Convention or series no.
Author(s) Knudsen B.B., Hametner C., Seycek O., Heese A., Koch H.U., Peters K.P.
Title Allergologically relevant rubber accelerators in single-use medical gloves
Bibliographic information July 2000, Vol.43, No.1, p.9-15. 25 ref.
Abstract Quantitative measurements of the residual amounts of rubber accelerators are needed to assist sensitized patients and consumers in selecting gloves. The aim of the study was to develop an analytical method by which rubber accelerators could be determined qualitatively and quantitatively. 19 different brands of single-use medical gloves were analysed for residual content of rubber accelerators, and the results were compared to manufacturers' claims. ZDEC, ZDBC, ZMBT and ZPC were the most frequently detected chemicals. Both phosphate buffer and acetone were tested as extraction media. No accelerators were detectable with the described chemical analysis in phosphate extracts, whereas acetone was demonstrated to be a technically suitable medium for extraction. However, further kinetic studies of the extraction procedure and skin penetration are needed to document that the extraction procedure simulates the clinical situation.
Descriptors (primary) protective gloves; latex; vulcanization accelerators; allergens
Descriptors (secondary) zinc diethyldithiocarbamate; acetone; zinc dibutyldithiocarbamate; thioamides; description of technique; chromatography; chemical analysis; solvent extraction
Document type D - Periodical articles
Country / State or ProvinceAustria; Germany; Denmark
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Hand and arm protection