| Document ID (ISN) | 76152 |
| CIS number |
01-257 |
| ISSN - Serial title |
0944-2502 - Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie |
| Year |
1998 |
| Convention or series no. |
|
| Author(s) |
Hollander A. |
| Title |
Laboratory animal allergy |
| Bibliographic information |
Nov. 1998, Vol.48, No.11, p.469-472. 9 ref. |
| Abstract |
Workers exposed to small experimental animals in research establishments were tested with 4 occupational allergens (rat urine, rat fur, mouse urine and mouse fur) and 5 common allergens (grass and tree pollen, cat and dog fur and house dust mites). Total IgE and specific IgE to rat and mouse urinary allergens were determined. The levels of exposure to respirable dust during specific tasks and the entire work shift were measured. A questionnaire was applied to determine the personal history of allergic symptoms, smoking habits and contact with laboratory and domestic animals. A total of 540 laboratory workers exposed to small experimental animals such as mice and rats participated in the study. A significant relationship between the level of exposure to rat urinary aeroallergens as well as atopy of laboratory workers and sensitization to rat allergens was found. A significant relationship was also observed between elevated total IgE and the occurrence of rat and mouse allergy. A higher prevalence of sensitization to rat allergens was found for male workers and smokers but this association was statistically not significant. |
| Descriptors (primary) |
laboratory work; allergies; experimental animals |
| Descriptors (secondary) |
smoking; skin allergies; epidemiologic study; cross-sectional study; sensitization; individual susceptibility; frequency rates; allergic respiratory disorders; sex-linked differences |
| Document type |
D - Periodical articles |
| Country / State or Province | Netherlands |
| Subject(s) |
Commerce, services, offices
|
| Broad subject area(s) |
Biological hazards
|
| Browse category(ies) |
Animal hazards
Allergies
|
