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Document ID (ISN)75746
CIS number 00-1669
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 1999
Convention or series no.
Author(s) Merget R., Topcu M., Friese K., Vormberg R., Fuchs T., Raulf-Heimsoth M., Breitstadt R.
Title A cross-sectional study of workers in the chemical industry with occupational exposure to hexamethylenetetramine
Bibliographic information Nov. 1999, Vol.72, No.8, p.533-538. Illus. 11 ref.
Abstract To assess the health effects of hexamethylenetetramine (HMT) on the airways and skin of workers in the chemical industry, a cross-sectional study was performed with 17 employees of a HMT-producing chemical plant and 16 control subjects from the plant, as well as 4 subjects who had left the production for medical reasons. A high proportion of exposed subjects and controls reported symptoms during the previous year, most of them were not related to work. Work-related symptoms and objective parameters did not show differences between groups. No cases of sensitization to HMT as assessed by skin prick tests or patch tests were found. Among those who had left the HMT production for medical reasons, 2 former workers showed sensitization to HMT by patch tests. These reported eczema during exposure but lost symptoms after removal from exposure. High exposures to HMT may cause allergic contact dermatitis. There was no evidence of an increased risk for occupational asthma.
Descriptors (primary) hexamethylenetetramine; chemical industry; dermatitis; skin allergies; asthma
Descriptors (secondary) eczema; cross-sectional study; sensitization; skin tests; respiratory function tests; allergy tests
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Chemical industry
Heterocyclic compounds
Skin diseases
Diseases of the respiratory system (except for pneumoconiosis & similar)