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CISDOC database

Document ID (ISN)75723
CIS number 00-1666
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1999
Convention or series no.
Author(s) Kanerva L., Alanko K., Jolanki R., Estlander T.
Title Airborne allergic contact urticaria from methylhexahydrophthalic anhydride and hexahydrophthalic anhydride
Bibliographic information Dec. 1999, Vol.41, No.6, p.339-341. Illus. 15 ref.
Abstract A 32-year-old atopic man began to work as a winder in an electrical machine manufacturing plant. Within a few months he developed rhinitis and conjunctivitis, but he waited 7 years before seeing a doctor about it. He also developed work-related pruritus and redness on his arms and face. He worked in an area where methylhexahydrophthalic anhydride (MHHPA) and hexahydrophthalic anhydride (HHPA) were used to harden epoxy resins. Patch testing was negative. An open application test showed a strong urticarial follicular reaction with MHHPA and a provocation test with this substance was positive. Provocation testing with HHPA was negative when diluted. Applied undiluted, HHPA provoked whealing. It was concluded that the patient had occupational allergic contact urticaria from MHHPA and HHPA. Occupational rhinitis from HHPA was also diagnosed from prick tests and RASTs. A change of job was recommended.
Descriptors (primary) allergens; hexahydrophthalic anhydride; urticaria; methyl hexahydrophthalic anhydride
Descriptors (secondary) epoxy resins; sensitization dermatitis; case study; skin tests; skin allergies; allergy tests; hardeners
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases