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CISDOC database

Document ID (ISN)75429
CIS number 00-1399
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Shaham J., Levi Z., Gurvich R., Shain R., Ribak J.
Title Hematological changes in hospital workers due to chronic exposure to low levels of ethylene oxide
Bibliographic information Aug. 2000, Vol.42, No.8, p.843-850. Illus. 41 ref.
Abstract A cross-sectional study was conducted to determine whether occupational exposure to low levels of ethylene oxide can cause haematological abnormalities. Blood samples were collected from a group of 47 exposed hospital workers and a control group, individually matched by age, sex and smoking habits, consisting of 88 hospital administration employees. Significant differences were found between the exposed and the control group in the frequency of workers with white blood cells lower than the normal range. An elevation in the absolute mean number of monocytes and eosinophils and a decrease in the absolute mean number of lymphocytes in the exposed group compared with the control group was found. An elevation in the percentage of haematocrit and the mean absolute number of the red blood cells, and a decrease in the mean absolute number of platelets, in the exposed group compared with the control group were also observed. A positive dose-response was found between cumulative dose exposure and the absolute mean number of eosinophils.
Descriptors (primary) ethylene oxide; haematological effects; health care personnel; hospitals
Descriptors (secondary) disinfection of equipment; cross-sectional study; blood cytology; dose-response relationship; long-term exposure
Document type D - Periodical articles
Country / State or ProvinceIsrael
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Blood diseases
Ethers
Ethylene oxide
Health care services