| Document ID (ISN) | 75429 |
| CIS number |
00-1399 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2000 |
| Convention or series no. |
|
| Author(s) |
Shaham J., Levi Z., Gurvich R., Shain R., Ribak J. |
| Title |
Hematological changes in hospital workers due to chronic exposure to low levels of ethylene oxide |
| Bibliographic information |
Aug. 2000, Vol.42, No.8, p.843-850. Illus. 41 ref. |
| Abstract |
A cross-sectional study was conducted to determine whether occupational exposure to low levels of ethylene oxide can cause haematological abnormalities. Blood samples were collected from a group of 47 exposed hospital workers and a control group, individually matched by age, sex and smoking habits, consisting of 88 hospital administration employees. Significant differences were found between the exposed and the control group in the frequency of workers with white blood cells lower than the normal range. An elevation in the absolute mean number of monocytes and eosinophils and a decrease in the absolute mean number of lymphocytes in the exposed group compared with the control group was found. An elevation in the percentage of haematocrit and the mean absolute number of the red blood cells, and a decrease in the mean absolute number of platelets, in the exposed group compared with the control group were also observed. A positive dose-response was found between cumulative dose exposure and the absolute mean number of eosinophils. |
| Descriptors (primary) |
ethylene oxide; haematological effects; health care personnel; hospitals |
| Descriptors (secondary) |
disinfection of equipment; cross-sectional study; blood cytology; dose-response relationship; long-term exposure |
| Document type |
D - Periodical articles |
| Country / State or Province | Israel |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Health care services
Blood diseases
Ethers
Ethylene oxide
|
