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Document ID (ISN)75398
CIS number 00-1396
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Garabedian M.J., Hoppin J.A., Tolbert P.E., Herrick R.F., Brann E.A.
Title Occupational chlorophenol exposure and non-Hodgkin's lymphoma
Bibliographic information Apr. 1999, Vol.41, No.4, p.267-272. Illus. 17 ref.
Abstract Occupational exposure to chlorophenols is suspected to increase non-Hodgkin's lymphoma (NHL) risk. This association was examined using data from a population-based case-control study of men aged 32 to 60 years. Potential chlorophenol exposure was characterized by intensity estimates and confidence ratings based upon review of verbatim job histories. Cases with substantial chlorophenol exposure had a significantly greater number of years of chlorophenol exposure; however, in conditional logistic regression models, the odds ratio for more than 8 years of substantial exposure was 1.51. Overall, the findings do not provide strong support for an association with NHL risk. Chlorophenol exposure in this study is not based upon measured values and, therefore, may fail to characterize actual chlorophenol exposures accurately. These results are consistent with other findings, which suggest that chlorophenol exposure is not likely to be a strong risk factor for NHL.
Descriptors (primary) lymphoma; chlorophenols; hazard evaluation
Descriptors (secondary) occupation disease relation; long-term exposure; questionnaire survey; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Blood diseases
Phenols and phenolic compounds
Alcohols
Risk evaluation